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Timothy L. Vollmer, MD
Department of Neurology
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Co-Director of the RMMSC at Anschutz Medical Center

Medical Director-Rocky Mountain MS Center
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Brian R. Apatoff, MD, PhD
Multiple Sclerosis Institute
Center for Neurological Disorders

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Weill Medical College of Cornell University

Clinical Attending in Neurology,
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Timothy L. Vollmer M.D.
Department of Neurology
University of Colorado Health Sciences Center
Co-Director of the RMMSC at Anschutz Medical Center
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Saturday

 

Give Winter the Boot






















By Laura Kolaczkowski

I caught myself looking at the big online seller site at a pair of Totes Winter Boots – nothing fancy but they would be quite functional for me. But then as I started to select my size and put a pair in my cart to check out a tiny voice in my head said ‘who are you kidding?’ I stopped and thought the voice is absolutely right, I don’t need those boots because if it is snowing enough that I need boots, I won’t be venturing out. Besides, they weren’t even cute boots but a plain old functional pair of Totes.
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Use of Ibudilast as MS Treatment Shows Enough Promise to Continue Trial



Ibudilast (MN-166) has shown enough promise as a treatment for progressive multiple sclerosis (MS) that its U.S. Phase 2b trial (NCT01982942) should continue, the U.S. National Institute of Health’s Data and Safety Monitoring Board has recommended.
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Friday

 

Look Beyond The Surface, A Plea To Those With And Without A Disease


















By Devin Garlit

Recently, I came across yet another story from a friend with MS about how they were discriminated against because of their handicapped parking placard. This is such a disheartening thing to read, and it’s something I keep hearing more and more about. You’ve no doubt heard or experienced it yourself: a nosy person sees you parking in a handicapped spot, can’t mind their own business, thinks they are the righteous hand of mob justice, and then confronts the person using the spot, never considering that the person, despite what they see, may suffer from an invisible illness. It’s devastating to those of us it’s happened to. With this scenario playing out time and time again, I wanted to again plead with folks to please look past what you see on the surface.
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FDA Extends Review of Ocrevus (Ocrelizumab) as Potential Treatment for Both Forms of MS Until March























The U.S. Food and Drug Administration recently extended until the end of March its review of the Biologics License Application (BLA) for Ocrevus. The application was submitted by Roche, requesting FDA approval for Ocrevus as a treatment for patients with relapsing-remitting multiple sclerosis (RRMS) and — for a first time — for those with primary progressive multiple sclerosis (PPMS) as well.
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Thursday

 

Oxidative Stress And MS: What's The Link Between The Two? The Details, Inside: VIDEO






























With the emergence of MS being put on record this year, how does oxidative stress contribute to it's prevalence? Can this be considered as one of the culprits of the said disease? Here's what experts have to say (Photo : Dan Kitwood/Getty Images)

A new study about patients with progressive MS has recently found that a steroid treatment can potentially be beneficial by decreasing oxidative stress in the cerebrospinal fluid. It was found that oxidative stress (OS) is currently perceived as a major subject for being a biomarker for the prevalence of MS and its progression. Consequently, experts have noted that these studies are showing a significant success rate at stopping and reversing the damage done by the demyelination caused by OS.
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Multiple Sclerosis Drugs Market : In-Depth Market Research and Trends Report 2015 – 2021




































Image Source: NEWSMAN

Wednesday, December 28th, 2016 - Persistence Market Research PVT. LTD.
MS is a nervous system disease which affects spinal cord and the brain. MS damages the myelin sheath. Myelin sheath is a term which exemplifies that material which surrounds and protects human nerve cells. This damage blocks messages between brain and the body and leads to the symptoms of MS. Some of the major symptoms of MS include thinking and memory problems, visual disturbances, problem in coordination and balancing of the body and muscle weakness.
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Wednesday

 

MS and Relationships





















Image Source: TEENAGEADVISOR

Sometimes MS puts you (at least me) into a position you might not expect… I have been asked to sit on an advisory committee that is putting together a retreat for couples where one partner has MS (I must admit the hilarity as I’ve had three remarkably unsuccessful relationships since my diagnosis)!
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Still Waiting on Ocrevus (Ocrelizumab): VIDEO





















Several months ago I wrote a blog on my personal website about Ocrevus, the first drug that’s designed specifically to treat primary progressive, as well as remitting, multiple sclerosis. The clinical trials for Ocrevus posted excellent results. The buzz in the medical community was good, and it was hoped that Ocrevus would receive final approval for use in the U.S. by the end of this year.
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Tuesday

 

Darwin Awards for the Disabled/Silly Stuff We Do When We’re Spacey and Forgetful





















By Kim Dolce

Many of you are probably familiar with the annual Darwin Awards. Invented by Wendy Northcutt, a UC Berkeley graduate with a degree in molecular biology, Northcutt explains the Darwin Awards as commemorating individuals who protect our gene pool by making the ultimate sacrifice of their own lives by eliminating themselves in an extraordinarily idiotic manner, thereby improving our species’ chance of long-term survival.
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Discovery of Brain-membrane Immune Cell May Advance MS Treatment Work














The discovery of a new type of immune cell in the membranes covering the brain is likely to advance understanding of the immune system’s impact on the brain, a study says. It could also lead to new treatments for MS and other neurodegenerative diseases.
Read more »

Monday

 

Insomnia – Physically Fatigued but Mentally Wide Awake


























Image Source: SLEEPTOLIVEINSTITUTE

By Matt Allen G

Fatigue is one of the most common and hated symptoms of MS affecting around 80% of patients (according to the National Multiple Sclerosis Society). It has become such a constant and debilitating part of my life that I honestly can not remember what it feels like to not have it; I can remember being able to go-go-go before MS but I can’t really remember how it physically felt to not have the weight of fatigue on my back from the moment I wake up till the moment I fall asleep. In the past, I have talked about the different types of fatigue (such as lassitude) and the possible causes but what I want to focus on today is one of my least favorite predicaments; feeling horribly fatigued all day and then spending the night as an insomniac.
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MS diagnosis leads local priest down an unexpected path






























The Rev. Joe Weigman, chaplain of the Sacred Heat Home in Oregon, has MS but says it has only strengthened his faith

In November of 1990, the Rev. Joe Weigman was a newly ordained transitional deacon in the Diocese of Toledo, on the path to become a priest. He was 29, in his final year of seminary at St. Meinrad in southern Indiana — about 10 miles from Santa Claus, Ind., and an hour away from Louisville. He was having some challenges with his legs and his balance, and was referred to a neurologist.
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Sunday

 

21st Century Cures Act Expected to Bring Real Change to MS Patients’ Lives















President Obama’s signing of the 21st Century Cures Act on Dec. 13 is expected to bring real change to those living with MS.
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Positive MS clinical trial suggests 'unprecedented' effects in relapsing form of the disease

















Stephen Hauser, MD, served as chair of the Scientific Steering Committee for the OPERA trials and is corresponding author on the NEJM paper reporting the results from those trials. Credit: Barbara Ries

In findings that show the effectiveness of a new strategy for treating MS, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab (brand name ) in both relapsing multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS).
Read more »

Saturday

 

Multitasking vs. Mindfulness
















The glory days of multitasking may be fading. More and more research points to the fact that our brains actually cannot multitask. Rather, the brain shifts rapidly (it’s all relative) back and forth between tasks as we attempt to do multiple activities at once.
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MS drug 'a landmark'























A drug that alters the immune system has been described as "big news" and a "landmark" in treating multiple sclerosis, doctors and charities say.

Trials, published in the New England Journal of Medicine, suggest the drug can slow damage to the brain in two forms of MS.
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Friday

 

The Torture That Is MS-Related Chronic Pain


















By Devin Garlit

I’ve been writing about my journey with MS for a while now. I’ve discussed a wide range of issues that I’ve dealt with over my many years with the disease. I have, however, held off on devoting an entire article to one of my worst symptoms until now. While I’ve made mention of it before, chronic MS-related pain is a symptom that I encounter every single day. It’s one that is hard to find relief from and it’s one that I know has a profound impact on who I am. For good and for bad, chronic pain can change you.
Read more »

 

New drug gives hope for those with progressive MS: VIDEO























Jerrie Gullick, who has multiple sclerosis.  CBS NEWS

As many as 400,000 Americans are believed to suffer from multiple sclerosis -- a debilitating disease of the central nervous system. A new drug may provide relief from the most devastating form of MS.
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Thursday

 

Ocrelizumab versus Interferon Beta-1a in Relapsing MS: STUDY






































Image Source: MEDICALPRESS
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Positive MS Clinical Trial Results Support New Treatment Approach
























Stephen Hauser, MD, served as chair of the Scientific Steering Committee for the OPERA trials and is corresponding author on the NEJM paper reporting the results from those trials. Photo by Barbara Ries

In findings that show the effectiveness of a new strategy for treating MS, researchers are reporting positive results from three large, international, multicenter Phase III clinical trials of the investigational drug ocrelizumab (brand name Ocrevus) in both relapsing multiple sclerosis (RMS) and primary progressive multiple sclerosis (PPMS).
Read more »

Wednesday

 

Which Vaccines Are Safe If You Have MS?



























Due to prior concerns that certain vaccines could induce a multiple sclerosis relapse, many people have naturally adopted a wary attitude when it comes to getting immunizations.
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Tips & Gadgets for People with MS or Other Physical Disabilities


























Sometimes life has a way of putting some seemingly insurmountable physical challenges in your path, especially if you are in a wheelchair. I like to think of myself as a problem solver, able to sometimes “outsmart” the problem by thinking outside of the box. A time when I had to use this “I can do this” mindset was an Easter dinner several years ago.
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Tuesday

 

Living with MS: the innovators working on ways to help millions battle MS


























The World vs.MS (TWvsMS) has been running since April and now enters its final phase. The initiative is designed to understand the daily challenges of living with MS, and help nurture ideas to solve them.
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Does vitamin D level at birth predict risk of MS?





























Lower levels of neonatal vitamin D may increase the risk of MS later in life.

MS is an unpredictable and often debilitating disease affecting over 2 million people worldwide. Although there is no known cure for the condition, researchers are investigating several avenues for treatment and prevention. New research suggests an intake of vitamin D during pregnancy may lower the risk of later-life multiple sclerosis in offspring.
Read more »

Monday

 

How Oxidative Stress Affects MS























Researchers are trying to pinpoint what oxidative stress does to people with multiple sclerosis and what treatments can help.

Oxidative stress (OS) as a biomarker for multiple sclerosis (MS) and disease progression is the subject of studies being conducted around the world.
Read more »

 

Santa race raies oney for MS Foundation of Madrid: VIDEO

































Image Source: AOL

Thousands of running Santas crowd through one of Madrid’s main boulevards on Saturday (December 17) as they take part in a six kilometre race in which amusement and Christmas where the main ingredients.
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Sunday

 

Trial Data Suggests RedHill’s Antibiotic Treatment May Benefit MS Patients

















Promising data from a small Phase 2a clinical trial sponsored by RedHill Biopharma for an antibiotic designed to fight certain infections suggests that adding the drug candidate to interferon treatment reduced relapse rates and brain lesion formation in patients with relapsing forms of MS.
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Researchers developing vaccine to prevent mono, MS: VIDEO
































A University of Minnesota professor and his team are developing a vaccine that could reduce the risk of mono, MS and certain cancers.
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