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Timothy L. Vollmer, MD
Department of Neurology
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Brian R. Apatoff, MD, PhD
Multiple Sclerosis Institute
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Weill Medical College of Cornell University

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Timothy L. Vollmer M.D.
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Saturday

 

At MS Poker Night, All Bets Are Off

























By Trevis Gleason

There have been a lot of bright, shiny moments in my life. For a good long time after my diagnosis with multiple sclerosis it seemed that those sparkles of life were no longer in my cards, but they did come back.
Read more »

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A Way Forward in Treating Primary-Progressive MS?




























Image Source: MEDIMAGAZIN

The lack of a medication to treat primary-progressive multiple sclerosis (PPMS) is a source of frustration for clinicians and patients. The results of a recent phase 3 study of the drug ocrelizumab may be cause for hope.
Read more »

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Measures of Subtle Movements While Standing Detects Neurologic Problems in MS Patients and Athletes with Concussions






















Researchers at Purdue University have developed a method of identifying subtle oscillations in a person’s posture that mirror an excessive delay in neuromuscular responses, indicating a neurologic deficit. The oscillations, which differ from the normal tendency of a standing person to sway, may aid in diagnosing neuromuscular disorders such as MS.
Read more »

 

MS disease activity link to food allergies studied































Multiple sclerosis disease activity link to food allergies has been studied. The findings of the study revealed that multiple sclerosis patients with a history of food allergies show an increase in disease activity.
Read more »

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Fatigue and Comorbidities in MS: STUDY


























Image Source: WHATISLYME
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Friday

 

Caution: Exercises Ahead















By Laura Kolaczkowski

Have you seen the ads running online these days that promote ten exercises for people with MS? Or ad that touts the eight ways for people with MS to strengthen our core and improve our balance? You probably have if you are on Facebook at all because they pop up regularly and they make me pause and question ‘what are they thinking!?’
Read more »

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Boston man with MS reaches new heights with support partner































Brian Moore-Ward
Image Source: HEALTHPROFESSIONALRADIO

Brian Moore-Ward recently climbed to the top of Boston’s tallest building to raise awareness for multiple sclerosis (MS). He has conquered this 60-flight climb seven years in a row.
Read more »

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Harsh out of necessity





































Image Source: CARCRASHLAWYER

To cope with multiple sclerosis, patients become morally stricter

Multiple Sclerosis affects nearly 2 and a half million people worldwide. It is a highly debilitating autoimmune disease: the condition severely reduces patients' quality of life through symptoms which disrupt motor, cognitive, and sensory systems. The disease, which in its most typical form is characterized by irregular remissions and acute attacks can create a state of increased anxiety in patients, and, according to scientists, can have negative cognitive/emotional effects as well, even influencing moral cognition in patients, as was observed in the recent study.
Read more »

 

Multiple Sclerosis Consortium Sets Up MS Clinical Trial Database of Patient Records for Research Use

























The Multiple Sclerosis Outcome Assessments Consortium (MSOAC) is making available to qualified researchers a new database containing almost 2,500 records of patients who were part of the placebo groups of nine MS studies.
Read more »

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Alterations of the optic pathway between unilateral and bilateral optic nerve damage in MS as revealed by the combined use of advanced diffusion kurtosis imaging and visual evoked potentials: STUDY



























Visual Evoked Potential Test
Image Source:  LOOKFORDIAGNOSIS
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Thursday

 

Ocrelizumab PPMS Trial Data Released, Offers Reasons for Hope and Concern: VIDEO





































Image Source: MULTIPLESCLEROSISNEWSTODAY

By Marc Stecker-Wheelchair Kamikaze

Last month, at the annual ACTRIMS (American Committee for Treatment and Research in Multiple Sclerosis) conference, the full trial results for the Ocrelizumab PPMS drug trial were finally revealed. These results had been much anticipated by the MS community, as there are currently no proven effective treatments for primary progressive multiple sclerosis, and many previous PPMS drug trials have ended in failure.
Read more »

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At-Home ‘Brain Training’ Program for MS Patients Reported to Improve Cognitive Skills by 29%




























Multiple sclerosis patients using a cognitive remediation computer training program, part of a controlled trial by researchers from NYU Langone Medical Center, had greater improvements in cognitive function than those who used a placebo-training program, according to a presentation at the recent American Academy of Neurology annual meeting in Vancouver, Canada.
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MS clinical trials – fighting for a cure






















To support the Multiple Sclerosis Trust’s Awareness Week 2016 the ISRCTN registry is exploring what’s new in the world of multiple sclerosis related clinical trials, and taking a look at some of the innovative studies in the registry.
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Drug boosts myelin regeneration in mice raising hope of future treatments for MS





























A new treatment for people suffering from MS may be on its way, scientists claim, after tests on mice showed promising results. The drug fluorosamine – not yet approved for use in humans – has the potential to boost myelin regeneration, a key step in curing patients.
Read more »

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Effects of motor-motor and motor-cognitive tasks on balance in patients with MS: STUDY




































Image Source: CLIPARTPANDA
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Wednesday

 

Men vs Women & Comorbidities























Image Source: MIRAGEWORLDOFWOMEN

By Laura Kolaczkowski

As if it’s not enough for so many of us to have multiple sclerosis, researchers from Canada have found evidence that we also have more than our fair share of other chronic diseases (comorbidities) to go with our MS. In a newly published study, Sex differences in comorbidity at diagnosis of multiple sclerosis: A population-based study, a research team led by Ruth Ann Marrie, MD, looked at the health conditions of over 23,000 people with MS at the time of their diagnosis compared to 116,638 people as matched controls (same sex and same age, but without multiple sclerosis). Their report focuses on the comorbidities of people who also have MS.
Read more »

 

Primary-Progressive MS Sleep Issues























Over half of people diagnosed with MS have sleeping problems. Fatigue is also one of the most common and persistent symptoms. While getting tired from time to time is normal for everyone, this extreme feeling of overexertion persists for those with MS.
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The Stages of Adjusting to a Diagnosis of MS




























There is no right or wrong way to adjust to a diagnosis of multiple sclerosis (MS.) Learning you have a chronic disease can bring up a number of emotions - fear, anger, denial, grief or guilt. Just as each person experiences the symptoms of MS differently, each person will also react to the diagnosis in their own unique way.
Read more »

 

Wrapping up MS
























Stephen Hauser, MD, the inaugural director of the new UCSF Weill Institute for Neurosciences, recently announced a breakthrough in his MS research that could change the lives of hundred of thousands of patients living with the neurological disease. Credit: Barbara Ries

With one drug to shut down its progression and another to undo its damage, plus a worldwide effort stalking the origins of multiple sclerosis, MS doesn't stand a chance.
Read more »

 

A pilot study of changes in functional brain activity during a working memory task after mSMT treatment: The MEMREHAB trial: STUDY





























Image Source: VANDERFILTUNIVERSITY
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Tuesday

 

What to Do When You’re Ready to Quit Smoking




























Image Source: ALQURANCLASSES

By Kim Dolce

You’ve read the studies on smoking and MS risk. Heck, you’ve read a lot of information about the negative effects of smoking. You’re a one- or two-pack a-day smoker and have been for a long time, you have MS, and your doctor has been telling you to quit for years. Now you think you’d like to try. But how do you do it?
Read more »

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Virtual reality game helps patients with MS: VIDEO























Virtual reality has been incorporated into physical therapy programs for quite some time. Now, a UTSA faculty member is using the technology in therapy pools to help people with multiple sclerosis.
Read more »

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New database for sharing MS clinical trial data








Image Source: CRITICALPATHINSTITUTE

A new database containing nearly 2500 patient records from the placebo arms of nine multiple sclerosis (MS) clinical trials is now available for research by qualified investigators. This is just one of the tools generated through the Multiple Sclerosis Outcome Assessments Consortium (MSOAC), a global effort launched by the National MS Society and Critical Path Institute (C-Path). MSOAC is striving to develop an outcomes measure that addresses the critical need for a more sensitive way to detect the benefit of potential treatments that slow or reverse progressive disability in people with MS.
Read more »

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The effect of postpartum intravenous immunoglobulins on the relapse rate among patients with MS: STUDY



















Image Source: pppmag.com
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The effects of prolonged wear of textured shoe insoles on gait, foot sensation and proprioception in people with MS: study protocol for a randomised controlled trial: STUDY





























Image Source: MULTIPLE-SCLEROSIS-RESEARCH
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Monday

 

MS Icebergs: What’s Going on in 90 Percent That Lies Beneath?






















At a meeting a few months ago, someone referred to multiple sclerosis as an “iceberg disease.” I jotted down a note to help me remember to write a blog about that idea. In shuffling through a file this week I ran across that note and I thought about it for a while.
Read more »

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MS: Taking Care of It and Living With It



























Julie Sancibrian
Photo by Karen Pike


Medical Therapies for Multiple Sclerosis

Proven studies still show that there is no single cause or cure for multiple sclerosis. Eighty  percent of patients with multiple sclerosis are diagnosed with remitting-relapsing, which means there is a recovery time (remitting) after experiencing symptoms (relapsing). A variety of treatments and therapies are available to help prevent relapses that would cause disability. However, if a patient is in one of the progressive stages, which means there is no recovery period and disability is present, then the only treatment, right now, are those to administer relief from symptoms such as pain and bladder problems.
Read more »

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Raising Awareness About Color Loss as a Potential Early Symptom of MS

























Color Vision Test Chart
Image Source: SMARTBRANDINGCO

An optometry practice in Mt. Pleasant, PA, H. Arnold Papernick OD, is raising awareness about the possibly of degrading color vision being an early warning sign of MS. The practice offers advanced eye functioning tests and exams, including color vision tests, which can potentially detect early signs of such issues.
Read more »

 

Editorial: Don't repeal protections against step therapy




























Sen. Jim Denning, R-Overland Park, center, helped speed up a bill regarding step therapy in February.
Image Source: THE CAPITAL-JOURNAL

Legislature shouldn't interfere with doctor-patient relationship

By The Capital-Journal Editorial Board
Imagine if your daughter was diagnosed with a terrifying, debilitating disease like multiple sclerosis. You consult with her doctor at length, consider an array of treatment options and finally choose one that proves effective.
Read more »

 

Tysabri (Natalizumab)-induced POU2AF1/Spi-B upregulation: STUDY

Sunday

 

MULTIPLE SCLEROSIS SUCKS!



















By Marc Stecker-Wheelchair Kamikaze

Allow me to apologize in advance for the contents of this essay. Quite simply, I’m fed up with multiple sclerosis and everything that has to do with multiple sclerosis. Those expecting to find any form of eloquence, wisdom, inspiration, or other redeeming qualities in these words will probably be sorely disappointed. Like a bulimic who just polished off a giant platter of lasagna, I’m feeling the need to purge and I have a hunch the results won’t be pretty. What follows promises to be more of a free-form rant than well-constructed discourse. I can’t guarantee any kind of narrative flow or grammatical cohesion, much less literary flourish or clever turn of phrase. No, instead I’m just gonna let it rip, an unadulterated regurgitation of everything about MS that’s been stuck in my craw these last few months. This may not be for the faint of heart, as I just might wander into some very uncomfortable territory. Okay, you’ve been warned; now’s the time to either buckle up or head for the exits.
Read more »

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My Top 5 MS Food Hacks





























I just picked up a T-shirt that says, “Eat Well and Travel Often.” It was obviously made just for me. Traveling to new places and seeing new things is something I enjoy tremendously. And enjoying delicious meals makes me feel pampered and cared for. But since I can’t travel to exotic destinations every week, eating well is something I spend more of my time thinking about.
Read more »

 

Biogen and AbbVie Present New Data Showing Zinbryta, an RRMS Drug Candidate, Aids Cognition Without Immune Depletion
































New data presented by Biogen and AbbVie at the recent 68th annual meeting of the American Academy of Neurology (AAN) showed that Zinbryta (daclizumab high-yield process) improved cognitive outcome measures in patients with relapsing forms of multiple sclerosis (RMS).
Read more »

 

A Multidimensional Computerized Adaptive Short-Form Quality of Life Questionnaire Developed and Validated for MS: The MusiQoL-MCAT: STUDY























Image Source: MDA/ALSNEWSMAGAZINE
Read more »

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The Efficacy of Functional Electrical Stimulation of the Abdominal Muscles in the Treatment of Chronic Constipation in Patients with MS: A Pilot Study: STUDY
























Image Source: NANDA-DIAGNOSIS
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Saturday

 

What To Do When Loved Ones Don’t Understand





























Image Source: LITTLE-BEAN-33

By Kim Dolce

Losing control of your body from multiple sclerosis can happen in a devastating series of losses over many years. But when your friends and family aren’t there for you, it’s a whole other kind of loss. What do you fear most—physical decline or abandonment? Decline would come as no surprise and there are things we can do to manage it. Rejection from a loved one can leave us feeling betrayed, helpless and unworthy. But there are ways we can weave a thread of connection with those we care for. Not all relationships can be salvaged, but we might develop a deeper, more authentic sense of connection with those that stay in—or come back to—the fold. Following is a compilation of thoughts from three bloggers with chronic illnesses.
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Aretha Franklin At Musical Moments For MS Gala: VIDEO




New Jersey Performing Arts Center (NJPAC) is offering a limited number of seats to see the Queen of Soul - Aretha Franklin on Thursday, June 16th at 7:30pm at a special price of $49.00 for the concert-only portion of the Musical Moments for Multiple Sclerosis Gala.
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Lymphoma Drug, Rituximab, Highly Effective in Treating Relapsing MS, Study from Sweden Reports



























Mabthera (rituximab), a widely approved drug for treating lymphoma and/or rheumatoid arthritis, is highly effective in treating multiple sclerosis (MS), researchers reported in an observational study in Sweden, where Mabthera is increasingly being used outside of its approved indications to treat relapsing-remitting MS patients. The study, published in the journal Annals of Neurology, is titled “Rituximab versus Fingolimod after Natalizumab in Multiple Sclerosis Patients.”
Read more »

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Metformin, pioglitazone reduce inflammation in MS with metabolic syndrome






















Image Source: DRUGS

In patients with multiple sclerosis who have metabolic syndrome, treatment with metformin and pioglitazone decreases disease activity exhibited on MRI, according to recent findings.
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Quality of Life in MS: STUDY
















Image Source:EESC.EUROPA
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Friday

 

Learning the Power of Saying NO When You Live With MS

















By Cathy Chester

As a writer I sit on my duff all day doing my job for various websites, including this one, plus writing my weekly blog posts. I love writing and do it so much that now I find myself writing entire sentences in my head while I watch TV, am on a date with my husband (sorry, honey) or even in my dreams.
Read more »

 

Dealing with MS: VIDEO























For Maureen McAler Wolf, dealing with multiple sclerosis isn’t a new challenge. She went to the doctor at 28 and got a message she’d heard before.
Read more »

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When Medical Marijuana Is Difficult To Access, 'Street Pharmacists' Are Some Patients' Only Hope: VIDEO





























Image Source: THEJOINTBLOG

As I wandered down Nostrand Avenue looking for the right building, he stood in the middle of the busy sidewalk, raised his left hand high, and waved in my direction.
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Atypical facial pain in MS caused by spinal cord seizures: a case report and review of the literature: STUDY


























Image Source: RAYUR
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Something Old, New, Borrowed, Blue: Anthracenedione Agents for Treatment of MS: STUDY
























Image Source: MDPI
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Thursday

 

Have You Done Your Homework?

















































Image Source: GOVGROUP

By Laura Kolaczkowski—April 19, 2016

No, I am not channeling your mother scolding you to crack the books and get your school work done.  Instead, I want you to be prepared for your next encounter with your doctor. As much as we might have delayed completing it in our school years, doing the homework is a critical part of every medical appointment these days. We are undergoing major changes in how healthcare is delivered to us and more than ever, as patients we have a responsibility to be an active participant in our care. This includes doing the often dreaded homework and there are a number of ways I do this.
Read more »

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Medicationdiscountcard.com Provides Prescription Coupons to Patients With MS: In Tandem With New Treatments















Image Source: MEDICATIONDISCOUNTCARD

Over 400,000 Americans live with Multiple Sclerosis (MS) every day with an estimated 10,000 new cases diagnosed each year. New therapies that slow the progression of this debilitating disease are beginning to give patients hope.
Read more »

 

Fibromyalgia vs. MS, comparing symptoms, diagnosis, and treatment






















While fibromyalgia and MS do share the symptom of pain, fibromyalgia is a musculoskeletal condition and multiple sclerosis is a neurological condition. There is still much unknown about the exact cause of fibromyalgia, but it is believed that the condition increases one’s sensitivity to pain. The cause of multiple sclerosis is the destruction of myelin, the protective coating surrounding nerves. Multiple sclerosis is an autoimmune disease, meaning, the body mistakenly attacks itself. Over time, due to myelin destruction, the nerves can no longer function properly, which results in a slew of symptoms.
Read more »

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Promising Phase 1 Trial Results of Stem Cell Therapy in Progressive MS Patients Being Presented at AAN Meeting



























Potentially groundbreaking research by the Tisch Multiple Sclerosis Research Center of New York (MSRCNY) will be presented on April 19 at the 68th American Academy of Neurology (AAN) Annual Meeting taking place in Vancouver, Canada. Dr. Saud A. Sadiq, director and chief research scientist at the Tisch center, will present results of a Phase 1 clinical trial of a stem cell therapy that showed promise in people with the progressive form of multiple sclerosis (MS).
Read more »

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Risk Factors for Suicidal Ideation in Patients Feeling Severely Affected by MS: STUDY








































Image Source: PINTEREST
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