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Timothy L. Vollmer, MD
Department of Neurology
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Co-Director of the RMMSC at Anschutz Medical Center

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Brian R. Apatoff, MD, PhD
Multiple Sclerosis Institute
Center for Neurological Disorders

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Weill Medical College of Cornell University

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Timothy L. Vollmer M.D.
Department of Neurology
University of Colorado Health Sciences Center
Co-Director of the RMMSC at Anschutz Medical Center
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Monday

 

Caregiver Perspective: What Resources Are Available If I’m Not Around Anymore?

















By Donna Steigleder—February 28, 2016

About this time last week, I was experiencing discomfort in my abdomen. As the hours progressed, the pain got worse until eventually it was so intense that I was vomiting. Unable to sit up, I was lying on the floor moaning in pain with no access to help within reach. Fortunately, Lynn heard my moaning and used his emergency response button to call for help. The dispatcher was able to summons the rescue squad and contact my daughter to come to our house to stay with Lynn until his son could arrive to take over (she has a special needs child she had to get home to before her husband left for work).
Read more »

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MS Society Funds Research Using Zebrafish to Observe CD46 Protein and Its Role in Brain Inflammation


In an innovative research project funded by the National Multiple Sclerosis Society, Dr. Anne Astier from the University of Edinburgh, U.K., and her team will use zebrafish to track the CD46 protein and determine where and how it affects the movement of immune cells into the brain, a process believed to influence multiple sclerosis (MS).
Read more »

 

Athletes race to top of 30 Rockefeller Plaza in 'Climb to the Top NYC' to raise money for MS

























Moritz Hafner, 31, was the fastest to the observation deck at the top of the building minutes after the sun rose.

Hundreds of New York athletes raced to the top of 30 Rockefeller Plaza Sunday to raise money for those suffering with multiple sclerosis.
Read more »

 

MS patients describe life after diagnosis































Image Source: HUBPAGES

Blurred vision, numbness, trouble speaking and difficulty walking are just some of the symptoms nearly half a million people across the US deal with on a daily basis, according to the Multiple Sclerosis Foundation.
Read more »

 

Systematic reviews in paediatric MS and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions: STUDY




















Image Source: MEDICALNEWSTODAY
Read more »

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Sunday

 

MS and Anxiety






















More than a third of people with MS experience anxiety disorders. Discover strategies to reduce anxiety and calm your worries.

The unpredictable nature of multiple sclerosis (MS) and the range of its symptoms make the disease challenging to deal with on many levels. Because you don't know when you might experience a relapse or how severe it may be, you might worry all the time about whether you'll be able to go to work, pick up your kids after school, or just make it to the bathroom when a flare occurs.
Read more »

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Welcome to the NEW mymsaa.org!




















By Multiple Sclerosis Association of America - MSAA

MSAA has completely redesigned our website, mymsaa.org! The newly revised site still includes all of the same detailed information about multiple sclerosis that you’ve come to depend on as part of the MS community.
Read more »

 

Stem Cell Transplant in MS: Next Steps
































Image Source: ABOUTTHEBRAIN

Could stem cell transplant emerge as a reliable treatment for both relapsing and progressive forms of multiple sclerosis (MS)? Experts believe so, and they hope to prove it in clinical trials.
Read more »

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MS Researchers Create a Nanoparticle Drug Able to Stop Inflammation and Autoimmune Attacks in Mice





























Researchers, working on an animal model and human cells, discovered a mechanism to halt autoimmune disease damage and developed of a novel class of drugs that triggers the mechanism, and which has the potential to treat autoimmune diseases like multiple sclerosis (MS) without impairing the normal and necessary activities of the immune system.
Read more »

 

Campath (Alemtuzumab) improves neurological functional systems in treatment-naive relapsing-remitting MS patients: STUDY






































Alemtuzumab Chemical Structure
Image Source: SCIENCEPHOTO
Read more »

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Saturday

 

A Trip to the Store; Sensory Overload


By Matt Allen G

It used to be so simple; “Oh no, I am out of milk”, so a quick trip to the store and I am back home with enough time to make breakfast and eat before I have to go to work. Not anymore. Let’s not even get into the whole rushing to work thing because, well, I am currently unable to hold a job. No, I want to talk about the going to the store bit. You see, it used to just be a quick walk to whatever aisle has whatever product I need and then a quick walk to the register, but now? Now it’s a huge endeavor, a journey! I don’t know how many of you have this but for me, this causes extreme sensory overload.
Read more »

 

Study: CCSVI may result from MS progression




































Image Source: LIQUIDAREA

A just released study on the relationship between multiple sclerosis (MS) and chronic cerebral venous insufficiency (CCSVI), a narrowing of the extracranial veins that restricts the normal outflow of blood from the brain, found that CCSVI may be a result of MS, not a cause.
Read more »

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Research on Progressive MS to Be Funded by International Progressive MS Alliance





















Image Source: AMSEL

Dr. Timothy Coetzee from the National Multiple Sclerosis Society will present an overview of the objectives and achievements of the International Progressive MS Alliance (PMSA), an organization dedicated to facilitating and funding research on progressive multiple sclerosis (MS), a form of MS especially lacking effective therapeutic options.
Read more »

 

TV doctor Dr Christian Jessen: My family's battle with MS






















TV doctor Dr Christian Jessen's explored a huge variety of health problems on but, until now, has never revealed a family tragedy caused by one condition - multiple sclerosis.
Read more »

 

Effect of Aerobic Training on Walking Capacity and Maximal Exercise Tolerance in Patients With MS: A Randomized Crossover Controlled Study: STUDY

Friday

 

Do You Have MS Pain?






























Image Source: MEDSCAPE

There are so many different ways in which multiple sclerosis pain manifests itself that I’m sometimes surprised that it took so long for MS doctors and researchers to recognize MS pain as a justified symptom.
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MS Social Network in UK, Shift.ms, Testing an Online Therapy Tool to Help People Deal with Stresses of Disease






Shift.ms, the U.K. social network dedicated to people with multiple sclerosis (MS), is testing a new tool designed to help people cope with the uncertainties and complex emotions that follow their diagnosis. The tool, called Thought Sort, is the first online cognitive behavioral therapy (CBT) specially designed for MS patients.
Read more »

 

Stem Cell Research Immune System / Vaccines Autism Regulatory Affairs / Drug Approvals Stem cell therapy: is the US missing a trick?





















Most stem cell therapies are not approved in the US, causing many Americans to travel abroad for treatment.

Autism, cerebral palsy, multiple sclerosis: they are all incurable diseases. But there is one treatment that may offer hope to patients with such conditions - autologous stem cell transplantation. In the US, however, this procedure is only used to treat patients with blood-forming disorders, meaning many Americans are traveling far and wide to countries where it is approved for their condition.
Read more »

 

New Protein, Anoctamin 2, Identified as a Target of Autoantibody Production in MS
























Researchers identified the chloride-channel protein anoctamin 2 (ANO2) as a new target for autoantibody production in multiple sclerosis (MS) patients. Their study, “Anoctamin 2 identified as an autoimmune target in multiple sclerosis,” was published in the Proceedings of the National Academy of Sciences of the United Sates of America (PNAS) journal.
Read more »

 

Multiparametric flow cytometric analysis of whole blood reveals changes in minor lymphocyte subpopulations of MS patients: STUDY



























Image Source: WEBMEDIA
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Thursday

 

Celebrating (Yes, Celebrating) My MSiversary
















By Devin Garlit—February 24, 2016

February will always be an important month to me. Sixteen years ago, on Groundhog Day, I was officially diagnosed with multiple sclerosis. It’s a day that changed not only my life, but the lives of everyone in my entire family. While it’s been a long and, at times, painful road for all of us, I still celebrate this anniversary, this MSiversary if you will, every year. It’s become a much bigger day to me then my birthday or any other holiday. While many might see this as a day they’d love to forget, I like see this as a day of hope and prefer to celebrate the good (yes, there are good) aspects of my life with MS.
Read more »

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Andrea Derlet From UC Davis: Team Approach Provides Benefits in MS Patient Care: VIDEO





















Treating a complicated condition like multiple sclerosis can require help from a variety of people in order to provide patients the best care possible. At UC Davis this approach includes a pharmacist on the clinic floor who can also help patients after hours.
Read more »

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7 Things You Don't Know About MS

























Unless you actually suffer from multiple sclerosis (MS) or have a close friend or relative who does, you probably know next to nothing about the disease. You might have heard that it has to do with the brain and that it can be pretty debilitating. Maybe you picture someone who's paralyzed or in a wheelchair, but you're not sure if that's accurate or if you might be at risk. (The Power Nutrient Solution is the first-ever plan that tackles the root cause of virtually every major ailment and health condition today.)
Read more »

 

Biomarkers May Predict Progression in MS




























Image Source: KPBS
Read more »

 

Comparison of energy consumption in different clinical forms MS with normal subjects (cohort study): STUDY





































Image Source: 3DSCANNERIMAGE
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Wednesday

 

Switching Roles


























Image Source: INSURANCEJOURNAL

By Laura Kolaczkowski—February 23, 2016

A number of you have talked about being both the person living with multiple sclerosis and are a caregiver for someone else. Recently I also shared this dual role. Normally my spouse and I with our own medical needs are able to take care of ourselves but his health had a couple major interruptions recently that forced that role to change.
Read more »

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Actress Rain Pryor, daughter of comedian Richard Pryor, reflects on growing up a biracial, half-Jewish child in Beverly Hills

























Rain Pryor's show, "Fried Chicken and Latkes," includes heartfelt material about her father's struggles with drugs and multiple sclerosis.
Read more »

 

MS Stem Cell Therapies Show Promise, But More Work Is Needed, Researcher Tells ACTRIMS 2016



























Dr. Andrew Goodman of the University of Rochester discussed the latest research and perspectives on stem cell strategies for people with multiple sclerosis (MS), saying in a presentation at the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2016 that such therapies, while promising, are not yet ready for widespread clinical use.
Read more »

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University Life: Sweet treat in trial to help reduce symptoms of MS


























Dr Shelly Coe and Prof Helen Dawes will be leading research at Oxford Brookes to see if a compound found in dark chocolate can help to reduce fatigue in people with MS

Back in November, the MS Society granted Oxford Brookes £75,000 to carry out a research project to assess whether pure hot chocolate can help to reduce the symptoms of Multiple Sclerosis.
Read more »

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Headaches in MS: Cross-sectional study of a multiethnic population: STUDY

Image Source: JESSICAGROSSLAC
Read more »

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Tuesday

 

Damn, My Long Relapse-Free Streak Has Ended






































Image Source: ANTI-INFLAMATORIOS

By Lisa Emrich—February 22, 2016

My journey with MS has had some significant ups and downs. Some of the downs include blindness, complete loss of use of two fingers on my left hand (which is devastating to a classically-trained pianist and teacher), weak arms and legs, all over numbness, impaired balance, fatigue, spasticity, anxiety, and depression.
Read more »

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People with MS "Can Do"





















Image Source: CANDOMULTIPLESCLEROSIS

It was unseasonably warm at Hunter Mountain on Saturday, but despite the warm weather, many skiers and others came to the mountain to do their part to help people with multiple sclerosis.
Read more »

 

Aging Ovaries May Signal Imminent Progression of MS
















Image Source: ULTRASOUNDTIPS


In women with multiple sclerosis (MS), ovarian aging is associated with a reduction in gray matter volume and higher levels of disability, independent of chronologic age and disease duration, a new study suggests.
Read more »

 

Patricia Coyle From Stony Brook University: Answering Questions About Progressive MS and More: VIDEO






















There are more than a dozen treatment options for patients with relapsing multiple sclerosis and so far none for the progressive form. Why that is and what can be done to change that are two of the biggest challenges in the field today.

Patricia Coyle, MD, from Stony Brook University discussed what progress is being made in the field of progressive multiple sclerosis, the different forms doctors are treating, and other challenges they face during the annual ACTRIMS conference in New Orleans.
Story Source: The above story is based on materials provided by HCPLIVE
Note: Materials may be edited for content and length

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Assessing the impact of MS disease activity and Zinbryta (daclizumab) HYP treatment on patient-reported outcomes: Results from the SELECT trial: STUDY




































Zinbryta Logo
Image Source: ZINBRYTA

Read more »

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Monday

 

Ocrevus on Fast-track for PPMS

















Image Source: NOVELHEALTHSTRATEGIES

By Laura Kolaczkowski—February 21, 2016

It was announced February 17, 2016, that the drug, ocrelizumab made by Roche and Genentech pharmaceutical companies, has been given Breakthrough Therapy Designation for the treatment of primary progressive MS by the Food and Drug Administration (FDA). Ocrelizumab studies Opera and Oratorio had positive results in treating a certain population of people with MS who were fairly early in their progression state and also in relapsing forms of MS. Ocrelizumab is the first investigation medicine to receive Breakthrough Therapy Designation, according to information from Genentech.
Read more »

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Predicting who will develop MS




























Demyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit: Marvin 101/Wikipedia

A team of investigators at Brigham and Women's Hospital (BWH) and the National Institute of Neurological Disorders and Stroke (NINDS) has launched a study of individuals at risk for multiple sclerosis (MS). By focusing on first-degree family members of MS patients, the research team seeks to better understand the sequence of events that leads some people to develop the disease. Their work also sets the stage for developing and testing interventions with which to block the onset of MS. The research team introduces the Genes and Environment in Multiple Sclerosis (GEMS) project, a large prospective natural history study, in a publication in the Annals of Neurology.
Read more »

 

Mark Freedman From University of Ottawa: Interferon Still a Viable Option for MS: VIDEO





















While newer medications are constantly being developed for multiple sclerosis one of the original options may still be the best for some patients.

Mark Freedman, HBSc, MSc, MD, from the University of Ottawa, discussed what he said some have described as a "defunct" treatment option during the annual ACTRIMS conference in New Orleans. There may be a rush to go with the newest and the most innovative medications as soon as they hit the market but Freedman said interferon is an option that doctors know works and has a decades long track record to back up its success as well as identify potential adverse events.
Story Source: The above story is based on materials provided by HCPLIVE
Note: Materials may be edited for content and length

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How to Handle MS Patients in the Emergency Department





















Image Source: GALLERYHIP

Trips to the emergency department (ED) can range from the most benign to the most serious of reasons.
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Should a psychotic or manic episode be considered an early manifestation of MS? A multiple case study: STUDY




































Image Source: WRITEOPINIONS
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Sunday

 

Guinness Cured My Multiple Sclerosis — Sort Of
































Image Source: ENJOYYOURHOLIDAY

By Trevis Gleason

Guinness cured my MS.

Not really, but I did feel better than I had in years during the winter of 2005-2006. That’s the period I write about in Chef Interrupted when I was living in a small town on the Irish coast… and I drank a fair good bit of the black stuff.
Read more »

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Country star Clay Walker says exercise keeps him moving through MS

























Country star Clay Walker, who has multiple sclerosis, says exercise keeps him limber.

Country music star Clay Walker hails from Texas, a state that loves its football. As a kid, when he wasn't playing quarterback he was on the basketball court or exploring the outdoors with his cousins. Always into fitness, he was shooting hoops back in 1996 when he discovered something was terribly wrong with his health.
Read more »

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MS patient to receive 'experimental' treatment in Russia





















Royce and Gabby Brewer at their wedding in April 2014.

A Canterbury man suffering from multiple sclerosis (MS) may get a second chance at a normal life after he receives an "experimental" treatment in Russia.
Read more »

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HIV and Lower Risk of MS: There is a Connection































Recently, researchers had discovered that HIV infection might decrease the risk of developing multiple sclerosis (MS).
Read more »

 

Nurse led telephone assessment of expanded disability status scale assessment in MS patients at high levels of disability: STUDY

































Image Source: MOTHERPEDIA
Read more »

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Saturday

 

Progressive MS in the News


























By Laura Kolaczkowski—February 19, 2016

The MS community was lit up in Fall 2015 about the news of ocrelizumab and its use in treating primary progressive MS – there was excitement everywhere with the thought that finally a treatment for this form of MS had  been proven effective. The  bright focus of the headlines quickly waned and we did not hear anything about this wonder drug until this week’s announcement by the Food and Drug Administration that Genetech and Roche, that the manufacturers of ocrelizumab, have received Breakthrough Therapy Designation, and will seek quick approval.
Read more »

 

MS sufferer splashes life savings on converting home - but now needs more help


























Struggle: Kate is appealing for donations from the public and the local community

Kate Tobin's condition has deteriorated so quickly that she now struggles to walk short distances, her sight has dimmed, and her speech has slowed considerably

Kate Tobin's condition has deteriorated so quickly that she now struggles to walk short distances, her sight has dimmed, and her speech has slowed considerably
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FOUNDATION SPOTLIGHT: ACT for MS



























ACT for Multiple Sclerosis offers exercise, education and mobility assistance programs for individuals living with MS.
Courtesy of ACT for Multiple Sclerosis

Since 2000, ACT for Multiple Sclerosis has been offering exercise, education and mobility assistance programs for individuals living with MS in the Coachella Valley.
Read more »

 

Results of New SPMS Study to Be Presented at ACTRIMS



























At the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum 2016, being held from Feb. 18–20 in New Orleans, LA, researchers have gathered to discuss “Progressive MS: Bench to Bedside and Back,” the meeting’s theme.
Read more »

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CRT-300.04 Does An Endovascular Procedure Improve the Quality of Life in Patients With MS: STUDY
























Image Source: PINTEREST
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