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Timothy L. Vollmer, MD
Department of Neurology
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Co-Director of the RMMSC at Anschutz Medical Center

Medical Director-Rocky Mountain MS Center
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Brian R. Apatoff, MD, PhD
Multiple Sclerosis Institute
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Weill Medical College of Cornell University

Clinical Attending in Neurology,
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Timothy L. Vollmer M.D.
Department of Neurology
University of Colorado Health Sciences Center
Co-Director of the RMMSC at Anschutz Medical Center
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Thursday

 

David and Alan Osmond fight MS together as father-son team: VIDEO







































Image Source: HEALTH

It's an unlikely occurrence in an unlikely family. Alan Osmond, one of the founding members of the iconic 1970s musical group The Osmonds, was diagnosed with Multiple Sclerosis. Then, his son David, now 36, has met with the same diagnosis.
Read more »

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Surviving the Holidays

















Image Source: BLAIRSAIR

By Laura Kolaczkowski—December 30, 2015

You know how fresh snow looks beautiful when it happens early in the season? I saw it this morning and now it is gone – there was just a little dusting of the snow outside to make the ground sparkle. The first measurable snowfall is always such a treat for me to see, even though I don’t like winter or the cold weather. The novelty of snow wears off quickly as the season drags out and I have to maneuver in the winter weather.
Read more »

 

The Potential for Neuronal Repair in MS: VIDEO

















The MD Magazine Peer Exchange "Modifying the Course of Multiple Sclerosis in New Ways: The Latest Advances in Treatment" features a distinguished panel of physician experts discussing key topics in multiple sclerosis (MS) research and management, including the latest insights into MS pathophysiology, new medication options and their application in clinical practice, and more.
Read more »

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High-dose vitamin D hope for MS





































Vitamin D has the potential to be an inexpensive, safe and convenient treatment for people with MS

High doses of vitamin D can dampen down the hyperactive immune response linked to multiple sclerosis (MS), a study has found.
Read more »

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Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive MS: STUDY

Wednesday

 

MS Fatigue, Cognitive Impairments Are Main Reasons Patients Lose Their Jobs
























Study investigates disease symptoms that most factor in employment status


Difficulties with cognitive function and fatigue are the main reasons patients with multiple sclerosis (MS) struggle to stay gainfully employed, a new study published in the December edition of the International Journal of MS Care has found. The study is titled “Factors Associated with Employment Status in Individuals with Multiple Sclerosis,” and authored by Margaret Cadden, MS, and Peter Arnett, PhD, from Pennsylvania State University.
Read more »

 

MS Patients Are Adequately, But Not Optimally, Treated for Depression


























Canadian study finds that access to antidepressant drugs is not alleviating depressive symptoms in many patients

A new Canadian study, published in the International Journal of MS Care, has concluded that the majority of patients with concurrent multiple sclerosis (MS) and depression are receiving antidepressant treatment. Despite this, however, many of these patients continue to report depressive symptoms.
Read more »

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I was a Child Ninja Truth Crusader: How I Tried to Debunk the Santa Myth and Other Stories

















































Image Source: BINGECRAFTER

By Kim Dolce—December 29, 2015
When I want your opinion, I’ll remove the duct tape. –Henny Youngman

The truth hurts, as we have all heard a million times since childhood. Our parents taught us that it is rude and makes people feel uncomfortable. We test this theory during early childhood in various ways.  Demanding full transparency, for example, was my M.O., which I repressed most of the time. But with Christmas comes childhood hysteria, that delicious, fantasy-drunk mania that we desperately try to reproduce with alcohol later in life. Drooling over a mountain of wrapped gifts usually brought my passion for the truth to its acme. I worked extra hard at keeping myself mute.
Read more »

 

B Cell Depletion Therapy Appears Effective for MS Therapy






























Better treatments for multiple sclerosis (MS) are closer than ever, such as B cell depletion therapy, according to findings published in Science Translational Medicine.
Read more »

 

Increased Incidence of MS in Systemic Sclerosis: a Nationwide Cohort Study: STUDY























Image Source: HEALTHLINE
Read more »

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Tuesday

 

Is MS Different in Women?






















Image Source: IMGARCADE

Anyone can get multiple sclerosis. But the disease has a gender gap that baffles experts.
Read more »

 

What Happened in Biotech in 2015?




















Image Source: CELGENE CORPORATION

Did the biotech industry have a good or bad year in 2015? Probably the best answer is "both." Halfway through 2015, biotech was booming. A couple of months later, though, investors were talking about a bear market for the industry. As the year winds down, things are looking up yet again. What happened in biotech during 2015? Here are three of the top stories.
Read more »

 

How MS Affects the Entire Family







































Image Source: CLIPARTPANDA

There's something about multiple sclerosis, or MS, that disrupts families at every level. "I've often talked about it as the uninvited guest," says Rosalind Kalb, vice president for health care information and resources at the National Multiple Sclerosis Society. "This disease shows up in your household, moves in, spreads its junk all over and doesn't leave. It means everyone has to develop a relationship with this intruder."
Read more »

 

MS Takes a Physical and Psychological Toll on Caregivers, Too





























Study finds younger adults often involved in care are also impacted at the workplace

People caring for multiple sclerosis (MS) patients can have substantial physical and psychological health concerns, and their care can adversely impact their employment, according to research findings recently published in the International Journal of MS Care. The study is titled “Care Partners and Multiple Sclerosis, Differential Effect on Men and Women.”
Read more »

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Baseline clinical status as a predictor of methylprednisolone response in MS relapses: STUDY


















Image Source: DAILYMED

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Monday

 

A new treatment for MS: “The drug has dramatic effects on relapsing MS”




























Symptoms come and go in most cases of multiple sclerosis (MS), a chronic disease in which the immune system attacks myelin, the nonconductive sheath that surrounds neurons’ axons. Yet 10 to 15 percent of cases are progressive rather than relapsing. This more severe version appears later in life and is marked by steadily worsening symptoms. No treatments are currently available, but that might be about to change.
Read more »

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Pascagoula woman's remarkable battle rewarded by national program

























Cassandra Lawson (right) and her daughters Verniah (left) and Elizabeth with some of the gifts brought to them by volunteers from Ingalls Shipbuilding through the National Multiple Sclerosis Society's "MS Santa" project. (MS Society photo)

It is impossible to have a conversation with Cassandra Lawson and not come away uplifted.
Read more »

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Facebook Favorites of 2015























Image Source: HMS-SOMERSET-CO

Many members of the MultipleSclerosis.net community actively participate in daily discussions on our Facebook page by commenting on our posts, posting questions on our page, and sharing our articles with others. Thanks to our community, we reach over 500,000 people every week!
Read more »

 

Anti-SPAG16 antibodies in primary progressive MS are associated with an elevated progression index




























Image Source: YOUTUBE
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Effect of Ampyra (Fampridine-PR / prolonged released 4-aminopyridine) on the manual functions of patients with MS: STUDY
















Image Source: DRUGS.COM
Read more »

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Sunday

 

In MS Study, Vitamin D Shown to Aid Myelin Repair: STUDY




























Early research finds vitamin's interaction with a protein retriggers nerve fiber protector

A new study in the Journal of Cell Biology suggests that vitamin D activates a receptor involved in myelin regeneration in patients with multiple sclerosis (MS). The study, entitled “Vitamin D receptor–retinoid X receptor heterodimer signaling regulates oligodendrocyte progenitor cell differentiation,” and was led by researchers at the University of Cambridge, United Kingdom.
Read more »

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MS was the only thing I focused on


























Image Source: DRBENTOWNSEND

By 1xeihfg—December 8, 2015

I was diagnosed in 2007 with RRMS. I worked 12 hr days 5-6 days a week as a QA Supervisor in a food plant. The only doctor I made time for was my Neurologist. She told me over a year ago to stop working and go on disability, my job was too stressful, I never took lunch or breaks.
Read more »

 

Eye cells grown at Johns Hopkins may lead to a cure for some forms of blindness






















Baltimore, Md. -- Dr Donald Zack, co-director of Center for Stem Cells and Ocular Regenerative Medicine at Johns Hopkins Wilmer Eye Institute, is leading a study that is growing eye cells in the lab and one day could help develop therapies that could stop blindness. Zach shows a cell sorter in his lab at the Smith Building. (Kim Hairston / Baltimore Sun)

Drs. Donald Zack and Valentin Sluch spent 30 anxious days waiting for their experiment to yield results.
Read more »

 

Can We Vaccinate Against PML in MS?























The JC polyomavirus is reported to be a persistent but otherwise asymptomatic kidney infection in a large portion of healthy people. However, in those with hereditary or acquired immune deficiency, a mutated form of the JC polyomavirus may lead to progressive multifocal leukoencephalopathy (PML), a central nervous system (CNS) infection characterized by progressive inflammation of the white matter of the brain. This is of particular interest in the treatment of multiple sclerosis (MS) with natalizumab (Tysabri), which has been associated with an increased risk for the development of PML.
Read more »

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Temporal lobe cortical pathology and inhibitory GABA interneuron cell loss are associated with seizures: STUDY























Image Source: LOOKFORDIAGNOSIS
Read more »

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Saturday

 

Silence is my name


















Image Source: CHRISTART

By Silence—December 16, 2015

What is in a name? My name is not really Silence, but Benjamin Franklin used it as a pseudonym, so can I. I am Silence and I have Multiple Sclerosis. At least doctors John Rose, Mateo Paz Soldan, and many other famous doctors told me so.
Read more »

 

THISability members offer each other support






















Image Source: IDAOTTAWA

After Ed Lent discovered he had multiple sclerosis, he kept his diagnosis secret for as long as possible.
Read more »

 

New MS Drug Shows ‘Excellent Profile’ in Preclinical Tests Against Approved Therapy



























Akaal Pharma's AKP-11 meets or surpasses MS drug Gilenya in animal model of disease

Akaal Pharma, a developer of small molecule drugs for the treatment of inflammation and autoimmune diseases including multiple sclerosis (MS), recently announced highly positive preclinical trial results on the safety and efficacy of its drug candidate AKP-11 when compared to Gilenya (fingolimod, FTY-720), an oral MS drug approved by the U.S. Food and Drug Administration (FDA) for the treatment of relapsing forms of the disease.
Read more »

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Experimental RRMS Therapy to Be Tested in a Phase 2b Clinical Trial























GeNeuro's GNbAC1 antibody targets a protein known to cause inflammation and neurodegeneration

GeNeuro SA, a company developing therapies for neurological and autoimmune disorders, recently announced the initiation of a Phase 2b clinical trial to assess its lead investigational antibody GNbAC1 in patients with relapsing-remitting multiple sclerosis (RRMS). The trial, called “CHANGE-MS,” plans to enroll 260 patients across 68 centers across the European Union and Eastern Europe.
Read more »

 

Level of education and MS risk after adjustment for known risk factors: The EnvIMS study: STUDY


























Image Source: VANISHREE2266
Read more »

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Friday

 

S. D. Anderson’s New Book “15 Minutes” is an Autobiographical Account of One Family’s Frustration and Determination Dealing with MS


































Recent release “15 Minutes”, from Page Publishing author S. D. Anderson, is an autobiography written in third person telling of S. D.’s personal battle with one of the most mysterious and unpredictable chronic conditions known to man: multiple sclerosis.

(PRWEB) DECEMBER 24, 2015

S.D. Anderson, a first time author and past president of the Tibetan KyiApso Club, LLC, has completed her book “15 Minutes”: a wonderful and eye opening memoir that details life with multiple sclerosis and it’s effect not only on her family and friends but all those involved in her care.

Read more »

 

Patients fear roadblocks as they enroll for medical marijuana program























Enrollment opens online as patients wait for doctors to register

Patients with severe illnesses can now begin enrolling in the New York State's Medical Marijuana Program.
Read more »

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Mahomet woman with MS 'going to get my life back'





















Photo by: Heather Coit/The News-Gazette
Taylor Lykins, sitting Thursday with her dog, Blizzard, displays an autographed blanket her Flippin’ Illini teammates want her to take to Chicago when she goes for a stem-cell transplant for her multiple sclerosis.

Like many young adults, Taylor Lykins holds down two jobs.
Read more »

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AFMW: Former Rockette and Former Miss New Hampshire Michelle Tolson

















FOX News Radio’s Tonya J. Powers spends “A Few Moments With…” Former Rockette and Former Miss New Hampshire Michelle Tolson.

As the holiday season is in full swing, I’m wondering if a segment with a former Rockette (and Miss New Hampshire, she was crowned with the title in 1996)-who has relapsing multiple sclerosis but still continues to dance-is of interest? After nearly seven years, Michelle Tolson stepped away from the grueling pace of a Radio City Rockette in 2002, but continued to pursue her love of dance. As a renowned dance instructor, Michelle now teaches throughout New York and New Jersey, and travels all over the country to teach on a competitive level. With such an active lifestyle, it came as a complete shock to Michelle when she was diagnosed with relapsing multiple sclerosis (MS) – a chronic and often debilitating disease – in 2014.
Story Source: The above story is based on materials provided by FOXNEWS
Note: Materials may be edited for content and length

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Pro-inflammatory pattern of IgG1 Fc glycosylation in MS cerebrospinal fluid































Cerebrospinal Fluid Cells
Image Source: JONLIEFFMD
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Thursday

 

The Unveiling of My MS
















By Meghan Pcsolyar—December 23, 2015

Telling people about my diagnosis was something I really struggled with. I was scared people would look at me differently and that I would be seen as the “sick girl.” My entire life, I have always wanted everyone to think that I’m “okay” no matter how I’m actually feeling; this of course carried over to how I initially reacted to having MS. My best friends and family knew and supported me through the six months where I was in limbo wrestling with my Clinically Isolated Syndrome (CIS) diagnosis. CIS is used to describe the first episode of neurologic symptoms caused by inflammation and demyelination in the central nervous system. During this time they were sworn to secrecy. I didn’t want anyone else to find out–secretly hoping it would never turn into MS–and so I didn’t want anyone else knowing anything!
Read more »

 

MS Patients Enjoy Yoga With a Volunteer




























Gail Pickens-Barger
Image Source: PINTEREST

PLEASANT GROVE, Utah, Dec. 23, 2015 /PRNewswire/ -- Gail Pickens-Barger is a doTERRA Elite Wellness Advocate, but that's just a small part of who she is and what she does for those in need. For 15 years Gail has helped hundreds of students improve their fitness levels as a Certified Yoga Instructor, however the students she serves today have different fitness goals than most because most of them suffer from Multiple Sclerosis (MS). MS is the most widespread disabling neurological condition of young adults around the world and the Multiple Sclerosis Foundation estimates that more than 400,000 people in the United States have MS. There is no cure for multiple sclerosis.
Read more »

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Identifying and avoiding wasteful or unnecessary medical tests

























Brian Callaghan, M.D., M.S., is helping lead a national push to determine what neurologic tests or services are performed more than they should be.
Credit: U-M Health System

Too many tests at the doctor's office could cost you more than just dollars. In addition to the huge hit to your wallet, there's also the potential harm of false positives, and just because a test has traditionally been done for a condition doesn't mean it's the best way to treat it.
Read more »

 

GeNeuro initiates GNbAC1 Phase IIb study in Relapsing-Remitting MS










Image Source: GENEURO

GeNeuro SA, a pioneer of new therapies for neurology and autoimmune disorders, announced today that it has initiated its planned Phase IIb study “CHANGE-MS” (Clinical trial assessing the HERV-W Env ANtagonist GNbAC1 for Efficacy in Multiple Sclerosis) with its lead antibody GNbAC1 in Relapsing-Remitting Multiple Sclerosis (RRMS). The study plans to enroll 260 patients in 68 clinical centers in the European Union and Eastern Europe. Preliminary results are expected by the end of 2017.
Read more »

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Immune response induced by Epstein–Barr virus and Mycobacterium avium subsp. paratuberculosis peptides in current and past infectious mononucleosis: a risk for MS: STUDY




































Epstein-Barr virus
Image Source: EPIBEAT
Read more »

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Wednesday

 

The Holidays: MS and Compromise



























By Laura Kolaczkowski—December 22, 2015

You know how fresh snow looks beautiful when it happens early in the season? I saw it this morning and now it is gone – there was just a little dusting of the snow outside to make the ground sparkle. The first measurable snowfall is always such a treat for me to see, even though I don’t like winter or the cold weather. The novelty of snow wears off quickly as the season drags out and I have to maneuver in the winter weather.
Read more »

 

With MS, I Miss the Office Holiday Party






















Ho, Ho, Ho! Where’s the V.O.?

The gifts are wrapped. The tinsel is strung. The Brussels sprouts are creamed, and the ugly sweater collected from the cleaner. Let the holiday festivities commence!
Read more »

 

Sued Over Old Debt, and Blocked From Suing Back
















































Clifford Cain Jr., a retired electrician in Baltimore, was used to living on a tight budget, carefully apportioning his Social Security and pension benefits to cover his rent and medication for multiple sclerosis.
Read more »

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MS Patients Show Better Gait and Balance with Ampyra (Dalfampridine) Treatment


























Withdrawal/reinitiation study expands on known walking speed benefits of approved MS therapy

In a new study, researchers evaluated the effect of dalfampridine treatment in people with multiple sclerosis (MS) and observed significant improvements in not only walking speed and distance, but also in gait and balance. The paper, titled “Dalfampridine Effects Beyond Walking Speed in Multiple Sclerosis,” was published in the International Journal of MS Care.
Read more »

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Identifying clues to molecular etiology of MS in South Indian patients: STUDY
































Image Source: WANNASURF
Read more »

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Tuesday

 

Fix It and Forget It? Re-evaluating Mood Disorder and Coping Behavior






























Image Source: HUFFINGTONPOST

By Kim Dolce—December 21, 2015

In my article titled “Thinking Out Loud: Emotional Stress or Brain Damage?” I explored the possible causes of my daily compulsion to deliver angry rants to an empty room. The article received several responses from people who engage in similar behavior and who see it as a healthy way of venting their pent up frustrations. These public affirmations made me examine more deeply my attitude about what is normal and what needs to be fixed.
Read more »

 

MS Australia & Mottainai Cycles Build ‘This Bike Has MS’ Via Grey Melbourne: VIDEO


The debilitating symptoms of multiple sclerosis (MS) have been hidden inside a bike in a new campaign launched today by Grey Melbourne.

The frame has been buckled and the wheels deliberately bent, teeth have been sheared off the gears and ball bearings tucked inside thin handlebar tape making this bike considerably difficult, erratic and uncomfortable to ride. A slightly twisted fork and the constant whirring sound from the gear cassette also feature on the bike built to aid awareness of MS and the upcoming MS Melbourne Cycle.
Read more »

 

MS Active and Inactive Lesions Differ in Levels of Enzymes that Drive Glucose Metabolism



















Study of key enzymes in energy metabolism may help in understanding of axonal degeneration

A research team recently showed that key enzymes of energy metabolism pathways are differentially expressed in active and inactive multiple sclerosis (MS) lesions, and may contribute to axonal degeneration in MS. The study, titled “Differential expression of glucose-metabolizing enzymes in multiple sclerosis lesions,” was published in the journal Acta Neuropathologica Communications.
Read more »

 

MS Researchers to Be Among 200 Specialists at January Symposium on Glial-Neuronal Interactions




























9th annual meeting of neuroscientists to look into latest research and findings

The upcoming 9th annual “Glial-neuronal Interactions in Health and Disease” symposium will bring together nearly 200 neuroscientists — focused on neuron and glial cell interaction and its affect on diseases such as multiple sclerosis (MS) — to discuss the latest findings in this area of brain research.
Read more »

 

Increased levels of CSF CD59 in neuromyelitis optica and MS: STUDY




























Image Source: LABOME
Read more »

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