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Timothy L. Vollmer, MD
Department of Neurology
University of Colorado Health Sciences Center Professor

Co-Director of the RMMSC at Anschutz Medical Center

Medical Director-Rocky Mountain MS Center
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Brian R. Apatoff, MD, PhD
Multiple Sclerosis Institute
Center for Neurological Disorders

Associate Professor Neurology and Neuroscience,

Weill Medical College of Cornell University

Clinical Attending in Neurology,
New York-Presbyterian Hospital
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Timothy L. Vollmer M.D.
Department of Neurology
University of Colorado Health Sciences Center
Co-Director of the RMMSC at Anschutz Medical Center
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Medical Director-Rocky Mountain MS Center


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Wednesday

 

Could Genentech’s Ocrelizumab Become the First Effective Primary Progressive MS Therapy?




























Genentech, a leading biotechnology company and member of the Roche Group, recently announced promising results on a pivotal Phase III clinical trial (ORATORIO) assessing its investigational therapy ocrelizumab as a treatment for patients with primary progressive multiple sclerosis (PPMS).
Read more »

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Caregiver Perspective: My World Is Very Structured
















































Donna Steigleder is a human resources professional by trade, nurse by training and caregiver for her husband, Lynn, who was diagnosed with MS in 2006. Donna now balances her time between her full-time job and caring for Lynn 24/7.  She shares her story to describe the challenges and triumphs associated with the life of a caregiver.

My world is very structured. I have a routine for almost everything so that I save time and don’t forget things. When my routine is in place and flowing, life is hard but it’s manageable. HOWEVER, let a little crisis get thrown in and it can tip me over the edge.
Read more »

 

The multiple benefits of the MS Readathon


























The MS Readathon is a great reason to encourage young people to read. Photograph: Thinkstock

Reading for pleasure helps children in many ways, and the MS Readathon is a great reason to get kids to start doing just that
Read more »

 

New! Fatigue Scale available now on My MS Manager mobile app

















































New version of My MS Manager now available for both Android and iOS devices!
Read more »

 

Effects of long-term whole-body vibration training on mobility in patients with MS: A meta-analysis of randomized controlled trials: STUDY
















































Image Source: KINETICINTEGRATIONS
Read more »

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Tuesday

 

Making Difficult Decisions: DMT






















Image Source: HUSHEDUCATION

Living with Multiple Sclerosis is a difficult journey to be on already, just from the symptoms, possibilities from exacerbation, and more. A lot of people (outsiders) don’t understand that those are just some of the difficult things we deal with.

Read more »

 

Drug Succeeds in Hard-to-Treat Form of MS































Switzerland's Roche has a potential new multi-billion-dollar drug to help it diversify beyond cancer treatments following the success of ocrelizumab against a hard-to-treat type of multiple sclerosis.
Read more »

 

FDA approves Bayer's electronic autoinjector for MS therapy



























The logo of Bayer AG is pictured at the Bayer Healthcare subgroup production plant in Wuppertal February 24, 2014.
REUTERS/INA FASSBENDER

The first electronic automatic injector to deliver a drug for the most common form of multiple sclerosis received approval from the U.S. Food and Drug Administration on Friday.
Read more »

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Status Update on MS Biomarkers






























Biomarkers are needed in multiple sclerosis (MS) to help with early diagnosis, estimate prognosis, and monitor treatment response, and a few candidates look promising, researchers reported.
Read more »

 

Spasticity in MS and role of glatiramer acetate treatment: STUDY































Image Source: MULTIPLESCLEROSISNEWSTODAY
Read more »

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Monday

 

MS signs are not always visible






























"Kiss Goodbye to MS" by MS Australia - http://www.kissgoodbyetoms.org/. Licensed under CC BY-SA 2.5 via Wikimedia Commons - https://commons.wikimedia.org/wiki/File:Kiss_Goodbye_to_MS.jpg#/media/File:Kiss_Goodbye_to_MS.jpg

So many signs of Multiple Sclerosis are visible to those around us. Obviously, if you are in a wheelchair or need devices to help you get around, it raises awareness of others. However, according to HealthCentral, there are five hidden signs even those with the disease are not fully aware of:
Read more »

 

Man runs from Canada to Florida for MS: VIDEO






















A man from Pennsylvania is running from Canada to Key West to raise awareness for multiple sclerosis. He was in Carteret County on Friday.
Read more »

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MS researchers correlate Brief International Cognitive Assessment for MS, performance of everyday life activities

















































Image Source: INFINITYENVISIONED

Kessler Foundation scientists found that the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) predicted performance of activities of daily living using Actual Reality™ (AR). The article, "Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) and performance of everyday life tasks," was published in Multiple Sclerosis Journal. The authors are Yael Goverover, PhD, OT, Nancy Chiaravalloti, PhD and John DeLuca, PhD.
Read more »

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Pilot Study of Natural Killer Cells in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and Multiple Sclerosis: STUDY





























Image Source: LERABLOG
Read more »

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Adherence and cost in MS patients treated with IM IFN beta-1a: impact of the CARE patient management program: STUDY







































Image Source: SKYLIGHT
Read more »

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Sunday

 

These Drugs Expose the Troubling Culture of Drug Pricing: VIDEO
























A lot of attention has been devoted to the details of pharmaceutical drug pricing, after the company Turing raised the price-per-pill of a 62-year-old drug exponentially overnight, earlier this week
Read more »

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Socializing & MS















Have you ever had someone tell you that you don’t like to go out, ever? Maybe you seem to like to stay home, instead of going out with friends? This is what I like to refer to in my previous article as, “I’m a Homebody”. However, this isn’t saying that I don’t want to go out and have fun with friends, but that I need to prepare for it, not do it all the time, etc.
Read more »

 

‘Amazing’ special sports program gives participants freedom, independence





























When Nancy Desiderio was younger, she preferred reading to physical activity.

But now that she’s older, and despite being afflicted with multiple sclerosis, she loves to tackle new challenges.
Read more »

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Possible JC Virus Vaccination Offers Important Implications for MS Treatment

























Two studies recently published in the journal Science Translational Medicine, revealed a possible new vaccine treatment for JC virus with important implications for multiple sclerosis (MS) treatment. The studies are entitled “JC polyomavirus mutants escape antibody-mediated neutralization” and “Broadly neutralizing human monoclonal JC polyomavirus VP1–specific antibodies as candidate therapeutics for progressive multifocal leukoencephalopathy.” The research was led by an international team of scientists at the National Cancer Institute in the United States, San Raffaele Scientific Institute in Italy, and University Hospital Zurich, University of Zurich, and Neurimmune Holding AG in Switzerland.
Read more »

 

Prevalence and risk factors for depression in women with MS: a study from Iran: STUDY

























Image Source: BLISSTREE
Read more »

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Saturday

 

Famished but Full: Digestive Problems and Their Relation to MS

Image Source: MISSADD


We who have MS are accustomed to experiencing sometimes daily changes in our body. We cope with pain, mobility problems, limb weakness, fatigue, and many other symptoms. It comes with the territory. Consequently, it’s hard to recognize changes as those worthy of a visit to the doctor.
Read more »

 

Bayer Receives FDA Approval for BETACONNECT - First and Only Electronic Autoinjector in Relapsing-Remitting Multiple Sclerosis (RRMS) Treatment































Bayer HealthCare announced today that the U.S. Food and Drug Administration (FDA) approved BETACONNECT, the first and only electronic autoinjector in the treatment of relapsing-remitting multiple sclerosis (RRMS). BETACONNECT will be available exclusively to BETASERON® (interferon beta-1b) patients beginning in early 2016.
Read more »

 

Brain-specific B Cells’ Reactivity Determines Glatiramer Acetate Therapy Success in MS Patients




























In a new study entitled “The brain antigen-specific B cell response correlates with glatiramer acetate responsiveness in relapsing-remitting multiple sclerosis patients,” a team of scientists discovered that differences in response to glatiramer acetate therapy among multiple sclerosis (MS) patients is potentially dependent on the presence of reactive brain-specific B cells in the patient’s blood. The study was published in the journal Scientific Reports.
Read more »

 

New Brain Cell Interaction Study Technique Could Impact MS Research


A study led by researchers from the University of Buffalo recently reported the development of a new method to study brain cell interaction more precisely. The study, published in the journal Nature Communications and entitled “Spatial mapping of juxtacrine axo-glial interactions identifies novel molecules in peripheral myelination,” could impact research into Multiple Sclerosis.
Read more »

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Olfactory bulb and olfactory sulcus depths are associated with disease duration and attack frequency in multiple sclerosis patients: STUDY






































Image Source: WIKIPEDIA
Read more »

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Friday

 

Can pregnancy and MS go together?





















Dr. Mariko Kita from Virginia Mason Neuroscience Institute gives us a brief overview of Multiple Sclerosis (MS), and the general worries that come with it, that include pregnancy.
Read more »

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Kent Kirkpatrick, city manager, stepping down in March for health reasons





























The City of Ottawa's long-time city manager, Kent Kirkpatrick, revealed he will not seek to extend his contract past March 2016 as balancing multiple sclerosis and work has become "more difficult over time."
Read more »

 

Medical Marijuana Use for Pain Relief in Medical Conditions like MS and AIDS Explored in New Nature Article



























Cannabis is a plant that can be used in a wide range of settings such as medical purposes, a source of fiber and oils, or as a recreational drug. Growing evidence has been reported on the clinical benefits of medical marijuana (herbal form) for treating chronic pain. Currently, several countries in the world and almost half of all U.S. states authorize the use of medicinal marijuana.
Read more »

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Progression confirmation period too short to define disability persistence in MS













































Image Source: MEGGIN

Researchers recommend extending the minimum timeframe for confirming disability progression in multiple sclerosis (MS) from 3–6 months to 12 or 24 months to better distinguish true irreversible disability from relapse-associated transient disability.

Read more »

 

Illness perception, treatment beliefs, self-esteem, and self-efficacy as correlates of self-management in MS: STUDY




































Image Source: YOURBUSINESS
Read more »

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Thursday

 

MS Hope helping those diagnosed with multiple sclerosis: VIDEO























He was diagnosed with MS at the age of 18 but has been symptom-free for the last two decades. Hear Matt Embry’s story in this interview with Kevin Stanfield.
Read more »

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Multiplex Analysis Approach to Discover Plasma-based, Progression Subtype-specific Biomarker Candidates for Multiple Sclerosis






























Multiple sclerosis is a common cause of neurologic disability in young adults. Based on the past course of MS disease, several patterns of progression or subtypes have been described. In recent years, growing evidence suggests the value of peripheral biomarkers in the diagnosis and prognosis of CNS disorders with the hope to improve clinical outcomes. We analyzed 120 protein biomarkers in plasma from 60 individuals with clinical diagnosis of the four subtypes of MS, including a control cohort. We identified several candidate biomarkers with significant plasma protein level changes in diseased vs. controls.  Although not conclusive, several candidate proteins show potential to distinguish among different subtypes of MS.
Click here to read original article

 

'Barney the Farm Dog' Connects Kids to Agriculture




























When he was diagnosed with multiple sclerosis, Vic Swiderski reminisced with his wife, Mary Lynn, about his time as a farmer and the animals he cared for on the farm near Brewer, as well as their special relationship with a St. Bernard named Barney.
Read more »

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Stanford offers lecture, books on living with multiple sclerosis


























Image Source: FLICKR

The human nervous system is a complex system that includes the brain, spinal cord and peripheral nerves. The nervous system works in conjunction with other body systems to keep us breathing, walking, talking and performing other vital functions.
Read more »

 

Karyopharm Advancing Neuroprotective SINE(TM) Compounds in Amyotrophic Lateral Sclerosis (ALS)





































Myelin Sheath
Image Source: MINIBUSSER
Read more »

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Wednesday

 

Answered prayers... the battle for multiple sclerosis medication


























Natalie Brennan had to battle to get the medicine she needs. Photo: Gerry Mooney

Natalie Brennan (26) fits the bill of the quintessential, modern young woman, living happily in a bustling metropolis. Though she is petite and has delicate features, she also looks fit and healthy. So it's something of a shock to learn that there have been times recently when she was too weak to walk, and others when it felt as if bubbles were exploding in her throbbing head.
Read more »

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MAD About MS: Tim the MS Bear






































Image: Tim on a train trip in 2013

Perhaps you are one of the almost 1,800 fans of Tim the MS Bear and his FaceBook page, or maybe you are just hearing about our furry friend for the first time. Tim the Bear’s page is a regular roundup of news items, blogs and other bits and pieces of MS news and words of support – he shares these items for people to learn more about MS and encourages people to ask questions about what they read.
Read more »

 

Biogen Inc (BIIB) Tecfidera PML Risk Unlikely To Affect Sales: Merrill Lynch: VIDEO

























Merrill Lynch analysts Ying Huang and Catherine Hu commented on the future prospects of Biogen Inc (NASDAQ:BIIB) in a research report dated September 21. They maintain a Buy rating on the stock, with a price target of $400, signifying a return potential of more than 27% over Friday’s close at $314.67 apiece.

Read more »

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Inhibiting LINGO-1 Protein is a Potential Future Treatment for Cognitive Impairment in MS Patients




























In a new study entitled “LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in experimental autoimmune encephalomyelitis mice”, a team of scientists report that the loss of myelin in multiple sclerosis (MS) patients’ brains contributes to their cognitive impairment. They showed that inhibiting protein LINGO-1 can ameliorate these cognitive deficits by promoting myelin growth, thereby establishing impairment of LINGO-1 as a potential new therapeutic avenue for cognitive deficits in MS patients.1 The study was published in the journal Science Reports.
Read more »

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How many injections did you miss last month? A simple question to predict interferon β-1a adherence in MS: STUDY

Tuesday

 

Multiple Sclerosis: Life after diagnosis































Image Source: BRUCEGILBERTMD

Multiple Sclerosis is often thought of as a woman’s disease. It is true that women are three times more likely to be diagnosed but the impact the condition can have on men can often be far greater. Jamie Martin of Auckland was 43 when he was diagnosed with Relapsing Remitting Multiple Sclerosis. Jamie was a healthy, happy husband and a father of two and his diagnosis rocked his world in ways he couldn’t imagine. "Within six months of my diagnosis my wife left me and took my gorgeous two children to live in Wellington," Jamie recounted. Like many couples and families the effect that Multiple Sclerosis can have on the family was too great.

Read more »

 

Politics of pot


Image Source: LERABLOG

Count Gov. Bruce Rauner among those who are skeptical of medical marijuana as a cure-all.
Read more »

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Review on Teriflunomide (AUBAGIO), an Oral Therapy for Relapsing Multiple Sclerosis





























Image Source: REUTERS

A review recently published in the journal Clinical Therapeutics focused on teriflunomide as a treatment for patients with relapsing multiple sclerosis (MS), taking into account its reported clinical efficacy and safety. The study is entitled “Teriflunomide: A Once-Daily Oral Medication for the Treatment of Relapsing Forms of Multiple Sclerosis” and was conducted by Dr. Aaron Miller, Professor of Neurology at Icahn School of Medicine at Mount Sinai, New York.
Read more »

 

Study Elucidating Multiple Sclerosis Seasonal Outbursts Might Aid in Lupus Treatment





























A team of researchers from Argentina and the U.S. have explained how flare-ups in multiple sclerosis patients are intimately related to their melatonin levels, a natural occurring hormone that regulates our sleep/wake cycles – circadian rhythms. The team showed that melatonin alleviates disease symptoms by resetting the immune system, with these finding holding important implications for other autoimmune diseases such as lupus and rheumatoid arthritis. The study, entitled “Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses”, was published in the Cell journal.
Read more »

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Association of Cortical Lesion Burden on 7-T Magnetic Resonance Imaging With Cognition and Disability in Multiple Sclerosis: STUDY





































Image Source: TOPNEWS
Read more »

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Monday

 

Cast of ‘Criminal Minds’ spotlights Multiple Sclerosis at 40th Annual Dinner Of Champions in Century City

























Check presentation to Julie Kaufer, National MS Society Southern California and Nevada Chapter President and Kim Phillips, National MS Society Southern California and Nevada Chapter Board Chair. Shemar Moore at podium and Keith Tisdale of Baby Girl.

Shemar Moore, best known for his role as FBI Special Agent Derek Morgan on the hit CBS show, “Criminal Minds,” was honored at the 40th annual Dinner of Champions, sponsored by and benefiting the National MS Society, Southern California and Nevada Chapter Thursday, Aug. 27 at the Century Plaza Hotel.
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Dog fight spawns GoFundMe effort to counter Rep. Kathy Watson





























Molly, a West Highland terrier pictured in this file photo, was given to Paula Witmer, a disabled woman in Rapho Township, Lancaster County, by state Rep. Kathy Watson after Witmer found the dog on a rescue website.

The battle over a rescued West Highland terrier that sparked a lawsuit this summer between Pennsylvania legislator Kathy Watson and a Lancaster County woman has spawned a countersuit and a GoFundMe site.
Read more »

 

East Lansing native partly blames football for diagnosis





























(Photo: Kirthmon F. Dozier, Detroit Free Press)

Kreg Palko’s favorite part of being a college football player was the crowds.
Read more »

 

Short Interest in Biogen Grows By 44.2% (BIIB)





























Shares of Biogen (NASDAQ:BIIB) were the recipient of a large growth in short interest during the month of August. As of August 31st, there was short interest totalling 3,860,160 shares, a growth of 44.2% from the August 14th total of 2,676,822 shares, Marketbeat.com reports. Approximately 1.6% of the company’s stock are short sold. Based on an average daily volume of 2,653,078 shares, the days-to-cover ratio is currently 1.5 days.
Read more »

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Teriflunomide: A Once-Daily Oral Medication for the Treatment of Relapsing Forms of MS: STUDY


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