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Saturday

 

Level of education and MS risk after adjustment for known risk factors: The EnvIMS study: STUDY


























Image Source: VANISHREE2266


Abstract

Background:
Several recent studies have found a higher risk of multiple sclerosis (MS) among people with a low level of education. This has been suggested to reflect an effect of smoking and lower vitamin D status in the social class associated with lower levels of education.

Objective:
The objective of this paper is to investigate the association between level of education and MS risk adjusting for the known risk factors smoking, infectious mononucleosis, indicators of vitamin D levels and body size.

Methods:
Within the case-control study on Environmental Factors In MS (EnvIMS), 953 MS patients and 1717 healthy controls from Norway reported educational level and history of exposure to putative environmental risk factors.

Results:
Higher level of education were associated with decreased MS risk (p trend = 0.001) with an OR of 0.53 (95% CI 0.41–0.68) when comparing those with the highest and lowest level of education. This association was only moderately reduced after adjusting for known risk factors (OR 0.61, 95% CI 0.44–0.83). The estimates remained similar when cases with disease onset before age 28 were excluded.

Conclusion:
These findings suggest that factors related to lower socioeconomic status other than established risk factors are associated with MS risk.

Story Source: The above story is based on materials provided by SAGEJOURNALS
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