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Tuesday

 

Non-Significant Associations Between Measures of Inhibitory Control and Walking While Thinking in Persons with Multiple Sclerosis: STUDY



















Abstract

Objective:
The current study examined if inhibitory control measures were associated with the dual-task cost (DTC) of walking in 28 persons with multiple sclerosis (MS) and 28 matched controls without MS.

Design:
Cross-sectional study

Setting:
University research laboratory

Participants:
The sample included 28 ambulatory persons with relapsing-remitting MS (median Expanded Disability Status Scale score = 3.0) from the local community (26 female, 2 male) and 28 controls matched by age, sex, body mass index, and education.

Interventions:
N/A

Main Outcome Measures:
All participants underwent a modified flanker task followed by four trials of the timed 25-foot walk. The first two trials involved walking as quickly as possible only (single-task condition), and the second two trials involved walking as quickly as possible while naming alternate letters of the alphabet (dual-task condition). Walking speed under single- and dual-task conditions was used to compute a DTC of walking.

Results:
Persons with MS demonstrated a similar DTC of walking compared with matched controls, but performed more poorly on inhibitory control measures. Interestingly, inhibitory control measures were not associated with DTC of walking in the MS sample (all |ρ|<.26, p>.19), but were associated with DTC of walking in controls (all |ρ|>.42, p<.03).

Conclusions:
Inhibitory control based on modified flanker performance might not be associated with DTC of walking in persons with MS.

Story Source: The above story is based on materials provided by ARCHIVESOFPHYSICALMEDICINEANDREHABILITATION
Note: Materials may be edited for content and length

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