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Timothy L. Vollmer, MD
Department of Neurology
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Medical Director-Rocky Mountain MS Center
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Multiple Sclerosis Institute
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Weill Medical College of Cornell University

Clinical Attending in Neurology,
New York-Presbyterian Hospital
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Timothy L. Vollmer M.D.
Department of Neurology
University of Colorado Health Sciences Center
Co-Director of the RMMSC at Anschutz Medical Center
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Monday

 
 Fine-tuned MRI may help MS diagnosis

 The research, published in the Proceedings of the National Academy of Sciences (PNAS), has found a way to improve a magnetic resonance imaging (MRI) approach called quantitative susceptibility mapping (QSM).

The scanning method could prove "an important tool for diagnosing and tracking the progression of multiple sclerosis (MS) and other neurological diseases," say the researchers from the Schulich School of Medicine & Dentistry at the University of Western Ontario, Canada.
The work was led by Ravi Menon, PhD, an expert in functional MRI (fMRI) with a Canada Research Chair in the subject.

They found this lack of sensitivity by changing the orientation of the MRI scanner signal, using a set up that rotated a rat's brain so that it could be scanned from 18 different angles.  The brains were then sent to the histology department for comparison. The scientists correlated scan data with these laboratory findings of "the microstructure of the brain" such as myelin concentration and integrity, and iron deposition.
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