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Tuesday

 

HERE'S 14 HEADLINES FROM TODAY'S NEWS

The effect of Nintendo(R) Wii(R) on balance in people with multiple sclerosis: a pilot randomized control study.  Interactive visual-feedback exercises such as Wii could be more effective than the current standard protocol in improving balance disorders in MS

 Clinically silent PML and prolonged immune reconstitution inflammatory syndrome in a patient with multiple sclerosis treated with natalizumab. This case shows that PML and IRIS can have a considerably variable course in natalizumab-treated MS patients and underlines the need for PML screening in JC virus antibody-positive patients in order to detect clinically silent cases.

Labor induction and augmentation in women with multiple sclerosis


 Anatomical brain connectivity can assess cognitive dysfunction in multiple sclerosis
  
Rare MEFV variants are not associated with risk to develop multiple sclerosis and severity of disease

 Relapse of multiple sclerosis in a patient retaining CCR7-expressing T cells in CSF under fingolimod therapy

 CXCL13 is a biomarker of inflammation in multiple sclerosis, neuromyelitis optica, and other neurological conditions

Relating health-related Quality of Life to disability progression in multiple sclerosis, using the 5-level EQ-5D
Conclusion: In its first reported use in an MS population, the EQ-5D-5L displayed good discriminatory capacity, although performance differed between the various domains of health, with evidence of a ceiling effect present in the domains of self-care and anxiety/depression. The EQ-5D-5L demonstrated a high correlation with EDSS in our MS cohort up to EDSS 6, after which point the utility valuation of severe health states exhibited much greater variability. Utility estimates from this study may be used in economic evaluations of disease-modifying therapies in MS, to inform resource-allocation decisions.

 TYSABRI/Natalizumab-induced autoimmune hepatitis in a patient with multiple sclerosis

The Multiple Sclerosis Intimacy and Sexuality Questionnaire -- re-validation and development of a 15-item version with a large US sample

Renal deterioration in multiple sclerosis patients with neurovesical dysfunction

Cognitive reserve in multiple sclerosis

MRI characteristics of familial and sporadic multiple sclerosis patients

Designing a pattern recognition system on GPU for discriminating between patients with micro-ischaemic and multiple sclerosis lesions, using MRI images

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