(Posted By: Josi Creek)


 "Demyelinating and inflammatory activities of MS persisted after allo-HSCT (allogeneic hematopoietic stem cell transplantation) in all of the patients with MS. Active and chronic active MS lesions exhibited significantly higher numbers of CD3⁺ T cells and CD8⁺ cytotoxic T cells and significantly higher scores of CD68⁺ microglia/macrophages than did chronic inactive lesions or normal-appearing white matter. The normal-appearing brains of allo-HSCT recipients who did not have MS were found to have significantly higher numbers of CD3⁺ T cells and CD8⁺ cytotoxic T cells and higher scores of CD68⁺ microglia/macrophages compared with the controls; however, no demyelination was identified in these non-MS samples."

Labels: Research, Stem Cell, Studies